Recombinant Rat C-X-C motif chemokine 5 protein (Cxcl5)
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中文名稱：Recombinant Rat C-X-C motif chemokine 5 protein(Cxcl5) (Active)
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品名簡稱：Recombinant Rat Scyb5 protein (Active)
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貨號：CSB-AP001431RA
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說明書：
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規格：￥852
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圖片：
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其他：
產品詳情
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純度：>97% as determined by SDS-PAGE.
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內毒素：Less than 1.0 EU/μg as determined by LAL method.
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生物活性：Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10-100 ng/ml.
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基因名：
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Uniprot No.：
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別名：Cxcl5; Scyb5C-X-C motif chemokine 5; Cytokine LIX; Small-inducible cytokine B5
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種屬：Rattus norvegicus (Rat)
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蛋白長度：Full Length of Mature Protein
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來源：E.Coli
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分子量：10.1 kDa
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表達區域：38-130aa
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氨基酸序列APFSAMVATE LRCVCLTLAP RINPKMIANL EVIPAGPHCP KVEVIAKLKN QKDNVCLDPQ APLIKKVIQK ILGSENKKTK RNALALVRSA STQ
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蛋白標簽：Tag-Free
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產品提供形式：Liquid or Lyophilized powder
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緩沖液：0.2 μm filtered PBS, pH 7.4 ,lyophilized
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：5-10 business days
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Datasheet & COA：Please contact us to get it.
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靶點詳情
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功能：May participate in the recruitment of inflammatory cells by injured or infected tissue.
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基因功能參考文獻：
- CRH suppressed CXCL5 production in glia via CRHR1 in the hippocampus of male rats. PMID: 29126185
- up-regulation of spinal CXCL5 and CXCR2 is involved in neuropathic pain after nerve injury, through regulating GSK-3beta activity in rats. PMID: 27717828
- Analysis of mitogen-activated protein kinases (MAPK) and glycogen synthase kinase (GSK3) pathways showed that they are involved in mechanisms of neuronal apoptosis in response to the depletion of CXCL5/LIX signaling. PMID: 22034072
- Data demonstrate that the chemokine CXCL5 is a peripheral mediator of UVB-induced inflammatory pain, likely in humans as well as rats. PMID: 21734176
- Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients. PMID: 18413816
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亞細胞定位：Secreted.
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蛋白家族：Intercrine alpha (chemokine CxC) family
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