CSF2
CSF2，即集落刺激因子2，別名粒細(xì)胞-巨噬細(xì)胞集落刺激因子（Granulocyte-Macrophage Colony-Stimulating Factor，GM-CSF）。它是一種由多種細(xì)胞類(lèi)型分泌的細(xì)胞因子，如巨噬細(xì)胞、T細(xì)胞、肥大細(xì)胞、自然殺傷細(xì)胞、內(nèi)皮細(xì)胞和成纖維細(xì)胞。CSF2的主要作用是促進(jìn)髓系造血祖細(xì)胞的增殖和分化，特別是對(duì)粒細(xì)胞和巨噬細(xì)胞系列的影響尤為顯著。它通過(guò)與其特異性受體結(jié)合，激活JAK/STAT信號(hào)通路，促進(jìn)細(xì)胞增殖、分化和成熟。CSF2在生物學(xué)上的意義非常重要，它對(duì)免疫系統(tǒng)的發(fā)育和功能至關(guān)重要。CSF2參與調(diào)節(jié)炎癥反應(yīng)、促進(jìn)組織修復(fù)和傷口愈合，并且在某些疾病的發(fā)病機(jī)制中也發(fā)揮作用，如類(lèi)風(fēng)濕性關(guān)節(jié)炎。此外，CSF2的異常表達(dá)或功能失調(diào)與多種疾病有關(guān)，包括某些類(lèi)型的癌癥和自身免疫疾病。在腫瘤微環(huán)境中，CSF2也可能影響腫瘤細(xì)胞的行為，包括增殖、侵襲和轉(zhuǎn)移。
熱銷(xiāo)產(chǎn)品
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (Active) (CSB-MP006045HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 28.1-63.8 pg/mL.
The purity of CSF2 was greater than 90% as determined by SEC-HPLC
CSF2 Antibodies
CSF2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA006043GA01HU | CSF2 Antibody | Human | ELISA,WB |
| CSB-PA06475A0Rb | CSF2 Antibody | Human | ELISA, IHC |
| CSB-PA06475B0Rb | CSF2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06475C0Rb | CSF2 Antibody, FITC conjugated | Human | |
| CSB-PA06475D0Rb | CSF2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA006045GA01HU | CSF2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA573559 | CSF2 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA268599 | CSF2 Antibody | Human,Mouse | ELISA,WB,IHC |
CSF2 Proteins
CSF2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-EP006045BO CSB-BP006045BO CSB-MP006045BO CSB-EP006045BO-B |
Recombinant Bovine Granulocyte-macrophage colony-stimulating factor (CSF2) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP006045BO | Recombinant Bovine Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast |
CSF2 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006045SH CSB-BP006045SH CSB-MP006045SH CSB-EP006045SH-B |
Recombinant Sheep Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006045RA CSB-EP006045RA CSB-BP006045RA CSB-MP006045RA CSB-EP006045RA-B |
Recombinant Rat Granulocyte-macrophage colony-stimulating factor (Csf2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006045DO CSB-EP006045DO CSB-BP006045DO CSB-MP006045DO CSB-EP006045DO-B |
Recombinant Dog Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-BP006045MO CSB-MP006045MO CSB-EP006045MO-B |
Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003441MO | Recombinant Mouse Granulocyte-macrophage colony-stimulating factor protein (Csf2) | E.Coli |
| CSB-AP003651MO | Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) (Active) | Mammalian cell |
| CSB-AP003661MO | Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) (Active) | E.coli |
CSF2 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006045CA CSB-EP006045CA CSB-BP006045CA CSB-MP006045CA CSB-EP006045CA-B |
Recombinant Cat Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP611263DSU CSB-EP611263DSU CSB-BP611263DSU CSB-MP611263DSU CSB-EP611263DSU-B |
Recombinant Chlorocebus aethiops Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP639041PI CSB-EP639041PI CSB-BP639041PI CSB-MP639041PI CSB-EP639041PI-B |
Recombinant Pig Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP717096GU CSB-EP717096GU CSB-BP717096GU CSB-MP717096GU CSB-EP717096GU-B |
Recombinant Guinea pig Granulocyte-macrophage colony-stimulating factor (CSF2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2 Proteins for Homo sapiens (Human)
CSF2 ELISA Kit
CSF2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E04568h | Human Granulocyte-Macrophage Colony Stimulating Factor,GM-CSF ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/mL |
CSF2 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E04569m | Mouse Granulocyte-Macrophage Colony Stimulating Factor,GM-CSF ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
CSF2 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E04570r | Rat Granulocyte-Macrophage Colony Stimulating Factor,GM-CSF ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
| CSB-E07340r | Rat Granulocyte Colony Stimulating Factor,G-CSF ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 7.81 pg/mL |
