Mouse Soluble Cluster of differentiation 30 ligand,sCD30L ELISA Kit
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中文名稱：小鼠可溶性CD30配體(sCD30L)酶聯免疫試劑盒
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貨號：CSB-E04715m
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規格：96T/48T
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價格：￥3200/￥2500
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其他：
產品詳情
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產品描述：小鼠可溶性CD30配體(sCD30L)酶聯免疫試劑盒（CSB-E04715m）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的TNFSF8含量。TNFSF8是重要靶點。它屬腫瘤壞死因子超家族，參與免疫調節。探索它與免疫細胞相互作用及信號傳導過程，期望通過調控它治療腫瘤、自身免疫病等，為開發新療法提供理論依據和方向。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于評估感染、自身免疫疾病等實驗模型中sCD30L的表達調控，為研究T細胞活化、淋巴組織發育及免疫相關疾病機制提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：Tnfsf8; Cd30l; Cd30lg; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD antigen CD153
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縮寫：
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Uniprot No.：
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種屬：Mus musculus (Mouse)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：0.156 ng/ml - 10 ng/ml
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靈敏度：0.039 ng/ml
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Others
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貨期：3-5 working days
產品評價
相關產品
靶點詳情
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功能：Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
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基因功能參考文獻：
- Altered expression of CD30L and IL-3 may be potential biomarkers for hepatotoxicity induced by D. bulbifera. PMID: 24647110
- It is shown here that CD30L knock out (KO) mice are highly susceptible to primary infection with Listeria monocytogenes as assessed by the survival rate. PMID: 21699557
- Modulation of CD30L/CD30 signaling by soluble CD30 could be a novel biological therapy for inflammatory diseases associated with Th17 responses. PMID: 21068411
- Characterization of the murine CD30 ligand (CD153) gene: gene structure and expression. PMID: 12392508
- CD30L is required for generation of long-lived memory CD8+ T cells; CD30L signaling triggers homing receptors for T(central memory) cells. PMID: 16177108
- Signaling executed by CD30positive T cell interaction with CD30Lpositive T cells plays a critical role in amplification of T helper type (Th)1 responses able to produce interferon-gamma against Mycobacterium bovis bacillus Calmette-Guerin infection. PMID: 18941223
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亞細胞定位：Membrane; Single-pass type II membrane protein.
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蛋白家族：Tumor necrosis factor family
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數據庫鏈接：
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