Ctsg Antibody
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中文名稱：Ctsg兔多克隆抗體
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貨號：CSB-PA006190LA01MO
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規格：￥440
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其他：
產品詳情
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產品名稱：Rabbit anti-Mus musculus (Mouse) Ctsg Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Ctsg antibody; Cathepsin G antibody; EC 3.4.21.20 antibody; Vimentin-specific protease antibody; VSP antibody
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宿主：Rabbit
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反應種屬：Mouse
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免疫原：Recombinant Mouse Cathepsin G protein (21-261AA)
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免疫原種屬：Mus musculus (Mouse)
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標記方式：Non-conjugated
本頁面中的產品，Ctsg Antibody (CSB-PA006190LA01MO)，的標記方式是Non-conjugated。對于Ctsg Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Cleaves vimentin. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa.
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基因功能參考文獻：
- these findings present evidence of an arterial-specific recruitment pattern centered on CatG-instructed adhesion strengthening. The inhibition of this process could provide a novel strategy for treatment of arterial inflammation with limited side effects. PMID: 27660294
- Cathepsin G activity may impair efferocytosis, which could lead to an accumulation of lesion-associated apoptotic cells and the accelerated progression of early atherosclerotic lesions to more complex lesions in Apoe(-/-) mice. PMID: 23934850
- SerpinB1 is critical for maintaining polymorphonuclear neutrophils survival by antagonizing intracellular cathepsin G activity. PMID: 23532733
- Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions. PMID: 22879591
- Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice. PMID: 22461690
- This is the first study showing a contribution of neutrophil-derived neutral serine proteases CG and NE to lung-protective immunity against focal pneumonia-inducing serotype 19 S. pneumoniae in mice. PMID: 21911460
- In the absence of a pathogen challenge, neutrophil-derived proteases and nucleosomes contribute to large vessels thrombosis, the main trigger of myocardial infarction and stroke. PMID: 20676107
- Inhibition of TGF-beta significantly reduces microvessel density in mammary tumor-induced bone lesions, mediated by decreased expression of both vascular endothelial growth factor (VEGF) and monocyte chemotactic protein (MCP)-1. PMID: 19646811
- neutrophil elastase and cathepsin G are inhibited by PAI-1 mutants PMID: 15131125
- cathepsin G activity at the tumor-bone interface plays an important role in mammary tumor-induced osteolysis through RANKL PMID: 18632634
- both Cat-G and PAR(4) play key roles in generating and/or amplifying relapses in ulcerative colitis PMID: 19528350
- Cathepsin G and MMP9 were identified as proteases involved in enhanced TGF-beta signaling at the tumor-bone interface of mammary tumor-induced osteolytic lesions. PMID: 19671689
- Serine protease required for resistance to microbial infection; contributes to pathogenessis in endotoxic shock PMID: 10714686
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亞細胞定位：Cell surface. Membrane; Peripheral membrane protein.
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蛋白家族：Peptidase S1 family
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組織特異性：In adult, detected only in bone marrow where expression is restricted to a small population of early myeloid cells.
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數據庫鏈接：
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