P4HB Antibody

Name: P4HB Antibody
Brand: CUSABIO
SKU: CSB-PA823188YA01DXU

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說明書

產品詳情

產品名稱：

Rabbit anti-Cricetulus griseus P4HB Polyclonal antibody
Uniprot No.：

Q8R4U2
基因名：

P4HB
別名：

P4HB antibody; PDIA1Protein disulfide-isomerase antibody; PDI antibody; EC 5.3.4.1 antibody; Prolyl 4-hydroxylase subunit beta antibody; p58 antibody
宿主：

Rabbit
反應種屬：

Cricetulus griseus
免疫原：

Recombinant Cricetulus griseus Protein disulfide-isomerase protein (20-509AA)
免疫原種屬：

Cricetulus griseus

標記方式：

Non-conjugated

本頁面中的產品，P4HB Antibody (CSB-PA823188YA01DXU)，的標記方式是Non-conjugated。對于P4HB Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA823188YB01DXU	P4HB Antibody, HRP conjugated	ELISA
FITC	CSB-PA823188YC01DXU	P4HB Antibody, FITC conjugated
Biotin	CSB-PA823188YD01DXU	P4HB Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
亞細胞定位：

Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein.
蛋白家族：

Protein disulfide isomerase family
數據庫鏈接：

KEGG: cge:100689433

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