RPAP2 Antibody
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中文名稱：RPAP2兔多克隆抗體
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貨號：CSB-PA004025
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規格：￥1090
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圖片：
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Western Blot analysis of 293 cells using RPAP2 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：RPAP2 antibody; C1orf82 antibody; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 antibody; EC 3.1.3.16 antibody; RNA polymerase II-associated protein 2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the C-terminal region of Human RPAP2.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
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基因功能參考文獻：
- These results suggest that RPAP2 controls Pol II activity through a direct interaction with Rpb6 PMID: 25639305
- During transcription of snRNA genes, Ser7 phosphorylation facilitates recruitment of RPAP2, which in turn both recruits Integrator and dephosphorylates Ser5. PMID: 22137580
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亞細胞定位：Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.
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蛋白家族：RPAP2 family
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數據庫鏈接：
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