Recombinant Chicken Tropomyosin alpha-1 chain (TPM1)

中文名稱：

雞TPM1重組蛋白
貨號：

CSB-YP024104CH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

雞TPM1重組蛋白
貨號：

CSB-EP024104CH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

雞TPM1重組蛋白
貨號：

CSB-EP024104CH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

雞TPM1重組蛋白
貨號：

CSB-BP024104CH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

雞TPM1重組蛋白
貨號：

CSB-MP024104CH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TPM1
Uniprot No.：

P04268
別名：

TPM1; Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1
種屬：

Gallus gallus (Chicken)
蛋白長度：

Full length protein
表達區域：

1-284
氨基酸序列

MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEERSKQLE DELVALQKKL KGTEDELDKY SESLKDAQEK LELADKKATD AESEVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAQKDEEK MEIQEIQLKE AKHIAEEADR KYEEVARKLV IIEGDLERAE ERAELSESKC AELEEELKTV TNNLKSLEAQ AEKYSQKEDK YEEEIKVLTD KLKEAETRAE FAERSVTKLE KSIDDLEDEL YAQKLKYKAI SEELDHALND MTSI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
基因功能參考文獻：
1. Structural analysis of smooth muscle tropomyosin alpha and beta isoforms. PMID: 22119916
2. The tendency of smooth muscle tropomyosin to form semi-rigid polymers with continuous and undampened rigidity may compensate for the lack of troponin-based structural support in smooth muscles. PMID: 20682264
3. An interaction between CHASM and tropomyosin, is demonstrated. PMID: 20627103
4. steady state actomyosin ATPase is inhibited by caldesmon and tropomyosin PMID: 16540476
5. All smooth muscle tropomyosins regulate binding to actin Tm in the same way. PMID: 17042503
6. role, in addition to its cooperative control of myosin function, establishes tropomyosin as a universal regulator of the multifaceted actin cytoskeleton PMID: 17569543
7. The results show that residues K5, K7, and D280 are essential to the stability of the alpha-tropomyosin complex. PMID: 18536019
8. The Mg(2+)-induced increase in stability of the C-terminal half of Tm is sensitive to mutations near the C-terminus. PMID: 19280641
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亞細胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

Tropomyosin family
數據庫鏈接：

KEGG: gga:396366

UniGene: Gga.4108