Recombinant Danio rerio R-spondin-1 (rspo1)

中文名稱：

斑馬魚rspo1重組蛋白
貨號：

CSB-YP724931DIL
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

斑馬魚rspo1重組蛋白
貨號：

CSB-EP724931DIL
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

斑馬魚rspo1重組蛋白
貨號：

CSB-EP724931DIL-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

斑馬魚rspo1重組蛋白
貨號：

CSB-BP724931DIL
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

斑馬魚rspo1重組蛋白
貨號：

CSB-MP724931DIL
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

rspo1
Uniprot No.：

Q6DHR0
別名：

rspo1; zgc:92153R-spondin-1; Roof plate-specific spondin-1
種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-261
氨基酸序列

D NLKASKARRQ RRISTEVPPS CSNGCEHCSE YNGCLKCRPR LFILLERNDI RQIGICLAAC PVGYYGIRNR DMNKCTQCKI ENCEACFSRN FCTKCKEGLY SHRGRCFSSC PEGFTVNGTM ECVVQCDLSE WSPWGPCMKK NKTCGFKKGN QTRTREPLQV PSPATSTGAA PASGCVPEIQ TQRCTVQKKI PCKGENKKNQ QNRGENSKNR GRDSKERGGN KKRKNTNRST TVPTITTSMV T
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway.
基因功能參考文獻：
1. hypothesized that misexpression of R-Spondin1 is necessary for AHR activation to block regeneration (R-Spondin1) PMID: 18495758
2. These preliminary findings suggest some aspects of RSPO1 like differential expression linked to sex determination may be conserved in fish while other aspects like subcellular localization differ from the mammalian RSPO1. PMID: 20349143
亞細胞定位：

Secreted.
蛋白家族：

R-spondin family
數據庫鏈接：

KEGG: dre:436625

STRING: 7955.ENSDARP00000058458

UniGene: Dr.161789