Recombinant Xenopus laevis Cellular tumor antigen p53 (tp53)

中文名稱：

有爪蟾蜍tp53重組蛋白
貨號：

CSB-YP024077XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍tp53重組蛋白
貨號：

CSB-EP024077XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍tp53重組蛋白
貨號：

CSB-EP024077XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍tp53重組蛋白
貨號：

CSB-BP024077XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍tp53重組蛋白
貨號：

CSB-MP024077XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

tp53
Uniprot No.：

P07193
別名：

tp53; Cellular tumor antigen p53; Tumor suppressor p53
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-363
氨基酸序列

MEPSSETGMD PPLSQETFED LWSLLPDPLQ TVTCRLDNLS EFPDYPLAAD MTVLQEGLMG NAVPTVTSCA VPSTDDYAGK YGLQLDFQQN GTAKSVTCTY SPELNKLFCQ LAKTCPLLVR VESPPPRGSI LRATAVYKKS EHVAEVVKRC PHHERSVEPG EDAAPPSHLM RVEGNLQAYY MEDVNSGRHS VCVPYEGPQV GTECTTVLYN YMCNSSCMGG MNRRPILTII TLETPQGLLL GRRCFEVRVC ACPGRDRRTE EDNYTKKRGL KPSGKRELAH PPSSEPPLPK KRLVVVDDDE EIFTLRIKGR SRYEMIKKLN DALELQESLD QQKVTIKCRK CRDEIKPKKG KKLLVKDEQP DSE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
基因功能參考文獻：
1. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53-overexpressed apoptotic embryos. [SAMDC] PMID: 16143307
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

P53 family
組織特異性：

Ubiquitous.
數據庫鏈接：

KEGG: xla:397926

UniGene: Xl.394