Recombinant Mouse Sodium/potassium-transporting ATPase subunit gamma (Fxyd2)

in vitro E.coli expression system

中文名稱：

小鼠Fxyd2重組蛋白
貨號：

CSB-CF009090MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

基因名：

Fxyd2
Uniprot No.：

Q04646
別名：

Fxyd2; Atp1c; Atp1g1; Sodium/potassium-transporting ATPase subunit gamma; Na(+/K(+ ATPase subunit gamma; FXYD domain-containing ion transport regulator 2; Sodium pump gamma chain
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區(qū)域：

1-70
氨基酸序列

MAGEISDLSANSGGSAKGTENPFEYDYETVRKGGLIFAGLAFVVGLLIILSKRFRCGGGK KHRQVNEDEL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
基因功能參考文獻：
1. FXYD2 activity may be a fundamental mechanism underlying the persistent hypersensitivity to pain induced by inflammation. PMID: 25633594
2. Data suggest that in pancreatic beta cells regulatory subunit of Na,K-ATPase FXYD2 plays a role in Akt signaling pathways associated with cell growth and proliferation. PMID: 23344951
3. The transcription factor Runx1 controls FXYD2 expression during the maturation of the somato-sensory system, partly through regulation of the tyrosine kinase receptor Ret. PMID: 22253804
4. Fxyd2 encodes three mRNAs that have tissue-specific expression patterns. PMID: 11526196
5. the gamma-subunit has an important role in the function of Na-K-ATPase to sustain the cellular cation balance over the plasma membrane in a hypertonic environment. PMID: 15572522
6. FXYD2 has a role in Na+ affinity and regulating thermal stability in mice PMID: 15755730
7. direct and critical role of the gamma-subunit on IMCD3 cell survival and/or adaptation in response to ionic hypertonic stress PMID: 16804105
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亞細胞定位：

Membrane; Single-pass type III membrane protein.
蛋白家族：

FXYD family
組織特異性：

Highest levels expressed in the kidney and spleen. Restricted to the basolateral membrane in renal epithelial cells and varies in its level of expression along the nephron.
數(shù)據(jù)庫鏈接：

KEGG: mmu:11936

STRING: 10090.ENSMUSP00000035429

UniGene: Mm.22742