CXCL1

CXCL1，全稱為Chemokine (C-X-C motif) ligand 1，是一種小分子的細(xì)胞因子，屬于CXC趨化因子家族。它也被稱為生長調(diào)節(jié)致癌基因α (GROα)、melanoma growth stimulating activity、alpha (MGSA-a)、NAP-3 或 SCYB1。CXCL1主要由巨噬細(xì)胞、中性粒細(xì)胞和上皮細(xì)胞表達(dá)，對中性粒細(xì)胞具有趨化作用，能夠吸引中性粒細(xì)胞遷移到感染或損傷部位。CXCL1通過與趨化因子受體CXCR2結(jié)合，參與炎癥反應(yīng)、傷口愈合和腫瘤形成等多種生理過程。在炎癥反應(yīng)中，CXCL1能夠促進(jìn)白細(xì)胞遷移到受損部位，增強(qiáng)單核細(xì)胞與內(nèi)皮細(xì)胞之間的粘附，刺激單核細(xì)胞的聚集和活化，并促進(jìn)單核細(xì)胞穿過內(nèi)皮細(xì)胞屏障，最終形成泡沫細(xì)胞，從而參與動脈粥樣硬化的形成。此外，CXCL1還與多種疾病的發(fā)生發(fā)展密切相關(guān)，如腫瘤、動脈粥樣硬化、風(fēng)濕性關(guān)節(jié)炎等。目前，針對CXCL1的藥物研發(fā)主要集中在抑制其活性或阻斷其與受體的結(jié)合，以期達(dá)到抗炎、抗腫瘤等治療目的。

熱銷產(chǎn)品

Recombinant Human Growth-regulated alpha protein (CXCL1) (CSB-EP006239HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CXCL1 Antibody

CXCL1 Protein

CXCL1 ELISA Kit

CXCL1 Antibodies

CXCL1 for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA09217A0Rb	Cxcl1 Antibody	Mouse	ELISA
CSB-PA09217C0Rb	Cxcl1 Antibody, FITC conjugated	Mouse

CXCL1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA06097A0Rb	CXCL1 Antibody	Human	ELISA
CSB-PA06097C0Rb	CXCL1 Antibody, FITC conjugated	Human
CSB-PA06097D0Rb	CXCL1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA006239GA01HU	CXCL1 Antibody	Human	ELISA,WB,IHC
CSB-PA009036	CXCL1 Antibody	Human,Mouse,Rat	IHC, ELISA

CXCL1 Proteins

CXCL1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239MO CSB-EP006239MO CSB-BP006239MO CSB-MP006239MO CSB-EP006239MO-B	Recombinant Mouse Growth-regulated alpha protein (Cxcl1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-RP092174m	Recombinant Mouse Growth-regulated alpha protein (Cxcl1), partial	E.coli
CSB-AP001061MO	Recombinant Mouse Growth-regulated alpha protein (Cxcl1)	E.Coli

CXCL1 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239RA CSB-EP006239RA CSB-BP006239RA CSB-MP006239RA CSB-EP006239RA-B	Recombinant Rat Growth-regulated alpha protein (Cxcl1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001391RA	Recombinant Rat Growth-regulated alpha protein (Cxcl1)	E.Coli

CXCL1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239HU CSB-BP006239HU CSB-MP006239HU CSB-EP006239HU-B	Recombinant Human Growth-regulated alpha protein (CXCL1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006239HU	Recombinant Human Growth-regulated alpha protein (CXCL1)	E.coli
CSB-AP000631HU	Recombinant Human Growth-regulated alpha protein (CXCL1)	E.Coli
CSB-EP006239HUa2	Recombinant Human Growth-regulated alpha protein (CXCL1)	E.coli

CXCL1 Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239SH CSB-EP006239SH CSB-BP006239SH CSB-MP006239SH CSB-EP006239SH-B	Recombinant Sheep Growth-regulated alpha protein (CXCL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCL1 Proteins for Cavia porcellus (Guinea pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239GU CSB-EP006239GU CSB-BP006239GU CSB-MP006239GU CSB-EP006239GU-B	Recombinant Guinea pig Growth-regulated alpha protein (CXCL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCL1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006239DXU CSB-EP006239DXU CSB-BP006239DXU CSB-MP006239DXU CSB-EP006239DXU-B	Recombinant Cricetulus griseus Growth-regulated alpha protein (CXCL1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCL1 ELISA Kit

CXCL1 ELISA Kit for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E09150h	Human growth-regulated oncogeneα/melanoma growth stimulating activity,GROα/MGSA ELISA Kit	serum, plasma, tissue homogenates	19.5 pg/ml

CXCL1 ELISA Kit for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E17286m	Mouse chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1) ELISA kit	serum, plasma, tissue homogenates	1.95 pg/mL