KIR2DS2
KIR2DS2，全稱(chēng)為殺傷細(xì)胞免疫球蛋白樣受體2DS2，是一種表達(dá)于自然殺傷細(xì)胞和部分T細(xì)胞表面的跨膜糖蛋白。該蛋白屬于KIR家族，與MHC-I類(lèi)分子結(jié)合，在調(diào)節(jié)NK細(xì)胞和T細(xì)胞的殺傷功能中發(fā)揮重要作用。KIR2DS2蛋白具有多種別名，包括CD158J、CD158b、KIR-2DS2、KIR2DL1、NKAT-5等。研究表明，KIR2DS2蛋白與多種疾病相關(guān)，如自身免疫病、病毒感染疾病、腫瘤、妊娠相關(guān)疾病等。近年來(lái)，KIR2DS2蛋白在免疫治療領(lǐng)域的應(yīng)用備受關(guān)注，相關(guān)藥物研發(fā)取得了一定的進(jìn)展。例如，針對(duì)KIR2DS2蛋白的抗體藥物已被用于治療某些腫瘤和自身免疫性疾病。此外，KIR2DS2蛋白的多態(tài)性也被用于移植免疫研究，以選擇合適的供體，提高移植成功率。
熱銷(xiāo)產(chǎn)品
KIR2DS2 Antibody (CSB-PA012360LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA012360LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA012360LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA012360LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
KIR2DS2 Antibodies
KIR2DS2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA012360LA01HU | KIR2DS2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA012360LB01HU | KIR2DS2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA012360LC01HU | KIR2DS2 Antibody, FITC conjugated | Human | |
| CSB-PA012360LD01HU | KIR2DS2 Antibody, Biotin conjugated | Human | ELISA |
KIR2DS2 Proteins
KIR2DS2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP012360HU1 CSB-EP012360HU1 CSB-BP012360HU1 CSB-MP012360HU1 CSB-EP012360HU1-B |
Recombinant Human Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012360HU | Recombinant Human Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2) | in vitro E.coli expression system |
