LCN2
LCN2，全稱為脂質(zhì)運(yùn)載蛋白2（Lipocalin-2），是一種分泌性糖蛋白，在人體內(nèi)多種組織中表達(dá)，包括肝、肺、腎、脂肪細(xì)胞、活化的中性粒細(xì)胞和巨噬細(xì)胞等。LCN2也被稱為中性粒細(xì)胞明膠酶相關(guān)脂質(zhì)運(yùn)載蛋白（NGAL）、24p3、siderocalin或中性粒細(xì)胞脂質(zhì)運(yùn)載蛋白（NL）。其作用機(jī)制多樣，涉及鐵的轉(zhuǎn)運(yùn)、調(diào)節(jié)免疫反應(yīng)、維持鐵穩(wěn)態(tài)和促進(jìn)上皮細(xì)胞分化等多個(gè)方面。LCN2通過螯合鐵來參與先天性免疫，限制細(xì)菌的生長。它也是腎損傷的生物標(biāo)志物，在慢性腎臟病、造影劑腎病和腎移植等疾病中發(fā)揮重要作用。此外，LCN2還與神經(jīng)系統(tǒng)疾病、肝臟疾病、呼吸系統(tǒng)疾病等多種疾病相關(guān)。目前，LCN2已被用作多種疾病的生物標(biāo)志物，并在藥物研發(fā)中展現(xiàn)出巨大潛力。例如，LCN2已被用作急性腎損傷（AKI）的早期診斷工具，以及阿爾茨海默病、血管性癡呆、帕金森病等神經(jīng)系統(tǒng)疾病的潛在治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Neutrophil gelatinase-associated lipocalin (LCN2) (Active) (CSB-AP000461HU)
驗(yàn)證數(shù)據(jù)
LCN2 Monoclonal Antibody (CSB-MA068302A0m)
驗(yàn)證數(shù)據(jù)
All lanes:Mouse anti-human Neutrophil gelatinase-associated lipocalin monoclonal antibody at 1μg/ml
Lane 1:NGAL transfected 293 cell lysate
Predicted band size : 22 kDa
Observed band size : 25 kDa
Immunohistochemical of paraffin-embedded human spleen organization using CSB-MA068302A0m at dilution of 1:200
Immunohistochemical of paraffin-embedded human prostate tissue using CSB-MA068302A0m at dilution of 1:200
LCN2 Antibodies
LCN2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA06834D0Rb | LCN2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA06836A0Rb | LCN2 Antibody | Human | ELISA, WB |
| CSB-PA06836D0Rb | LCN2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-MA068302A0m | LCN2 Monoclonal Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA06837A0Rb | LCN2 Antibody | Human | ELISA |
| CSB-PA06837B0Rb | LCN2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06837C0Rb | LCN2 Antibody, FITC conjugated | Human | |
| CSB-PA06837D0Rb | LCN2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA076130 | LCN2 Antibody | Human | ELISA,IHC |
| CSB-PA171092 | LCN2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA06834A0Rb | LCN2 Antibody | Human | ELISA, WB |
LCN2 for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA012816LA01RA | Lcn2 Antibody | Rat | ELISA, IHC |
| CSB-PA012816LB01RA | Lcn2 Antibody, HRP conjugated | Rat | ELISA |
| CSB-PA012816LC01RA | Lcn2 Antibody, FITC conjugated | Rat | |
| CSB-PA012816LD01RA | Lcn2 Antibody, Biotin conjugated | Rat | ELISA |
LCN2 Proteins
LCN2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012816MO CSB-EP012816MO CSB-BP012816MO CSB-MP012816MO CSB-EP012816MO-B |
Recombinant Mouse Neutrophil gelatinase-associated lipocalin (Lcn2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LCN2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012816RA CSB-EP012816RA CSB-BP012816RA CSB-MP012816RA CSB-EP012816RA-B |
Recombinant Rat Neutrophil gelatinase-associated lipocalin (Lcn2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
LCN2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-AP000461HU | Recombinant Human Neutrophil gelatinase-associated lipocalin (LCN2) (Active) | E.Coli |
LCN2 ELISA Kit
LCN2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09408h | Human neutrophil gelatinase-associated lipocalin,NGAL ELISA Kit | serum, plasma, urine, tissue homogenates | 3.9 pg/mL |
LCN2 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09410m | Mouse neutrophil gelatinase-associated lipocalin,NGAL ELISA Kit | serum, plasma, tissue homogenates, urine | 3.12 pg/mL |
LCN2 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09409r | Rat neutrophil gelatinase-associated lipocalin,NGAL ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/ml |
