PYCARD
Apoptosis-associated speck-like protein containing a CARD is a protein in humans that is encoded by PYCARD gene. Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3. Involved in macrophage pyroptosis, a caspase-1-dependent inflammatory form of cell death and is the major constituent of the ASC pyroptosome which forms upon potassium depletion and rapidly recruits and activates caspase-1. In innate immune response believed to act as an integral adapter in the assembly of the inflammasome which activates caspase-1 leading to processing and secretion of proinflammatory cytokines.
PYCARD Antibodies
PYCARD for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA019114GA01HU | PYCARD Antibody | Human | ELISA,WB,IHC |
| CSB-PA000940 | PYCARD Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA890936LA01HU | PYCARD Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA890936LB01HU | PYCARD Antibody, HRP conjugated | Human | ELISA |
| CSB-PA890936LC01HU | PYCARD Antibody, FITC conjugated | Human | |
| CSB-PA890936LD01HU | PYCARD Antibody, Biotin conjugated | Human | ELISA |
PYCARD Proteins
PYCARD Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP810219BO CSB-EP810219BO CSB-BP810219BO CSB-MP810219BO CSB-EP810219BO-B |
Recombinant Bovine Apoptosis-associated speck-like protein containing a CARD (PYCARD) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PYCARD Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP861664MO CSB-MP861664MO CSB-EP861664MO-B |
Recombinant Mouse Apoptosis-associated speck-like protein containing a CARD (Pycard) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP861664MO | Recombinant Mouse Apoptosis-associated speck-like protein containing a CARD (Pycard) | E.coli |
PYCARD Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP862308DIL CSB-EP862308DIL CSB-BP862308DIL CSB-MP862308DIL CSB-EP862308DIL-B |
Recombinant Danio rerio Apoptosis-associated speck-like protein containing a CARD (pycard) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PYCARD Proteins for Homo sapiens (Human)
PYCARD ELISA Kit
PYCARD ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL019114HU | Human Apoptosis-associated speck-like protein containing a CARD(PYCARD) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
PYCARD ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL019114MO | Mouse Apoptosis-associated speck-like protein containing a CARD(PYCARD) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 1.95 pg/mL |
