TFF1
TFF1，全稱為轉(zhuǎn)鐵蛋白受體樣因子1（Trefoil factor 1），是一種主要由胃腸道黏膜細(xì)胞產(chǎn)生的蛋白質(zhì)，也被稱為pS2或MUC21。TFF1蛋白在維持胃腸道黏膜的完整性方面發(fā)揮著重要作用，它能夠增強(qiáng)黏液凝膠的穩(wěn)定性，為胃腸道提供重要的物理屏障，保護(hù)其免受潛在傷害。此外，TFF1蛋白還參與傷口愈合過程，通過加速傷口愈合來局部抵抗炎癥和胃腸道損傷。在疾病方面，TFF1蛋白的表達(dá)水平與多種胃腸道疾病相關(guān)，如炎癥性腸病、胃癌等。目前，針對(duì)TFF1蛋白的藥物研發(fā)也在進(jìn)行中，例如一些靶向TFF1的單克隆抗體藥物已進(jìn)入臨床試驗(yàn)階段，用于治療炎癥性腸病等疾病。
熱銷產(chǎn)品
Recombinant Human Trefoil factor 1 (TFF1) (CSB-EP023431HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023431HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TFF1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023431HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TFF1.
TFF1 Recombinant Monoclonal Antibody (CSB-RA844006A0HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescence staining of HepG2 cell with CSB-RA844006A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Overlay Peak curve showing MCF-7 cells stained with CSB-RA844006A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
TFF1 Antibodies
TFF1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA023431GA01HU | TFF1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA023431DSR2HU | TFF1 Antibody | Human | ELISA, IHC |
| CSB-PA617703 | TFF1 Antibody | Human | ELISA,WB |
| CSB-PA160693 | TFF1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-RA844006A0HU | TFF1 Recombinant Monoclonal Antibody | Human | ELISA, IF, FC |
TFF1 Proteins
TFF1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023431HU | Recombinant Human Trefoil factor 1 (TFF1) | Yeast |
| CSB-EP023431HU | Recombinant Human Trefoil factor 1 (TFF1) | E.coli |
| CSB-AP000341HU | Recombinant Human Trefoil factor 1 protein (TFF1) | E.Coli |
| CSB-BP023431HU CSB-MP023431HU CSB-EP023431HU-B |
Recombinant Human Trefoil factor 1 (TFF1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFF1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023431RA CSB-EP023431RA CSB-BP023431RA CSB-MP023431RA CSB-EP023431RA-B |
Recombinant Rat Trefoil factor 1 (Tff1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFF1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023431DO CSB-EP023431DO CSB-BP023431DO CSB-MP023431DO CSB-EP023431DO-B |
Recombinant Dog Trefoil factor 1 (TFF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TFF1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023431MO CSB-EP023431MO CSB-BP023431MO CSB-MP023431MO CSB-EP023431MO-B |
Recombinant Mouse Trefoil factor 1 (Tff1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
