ULBP2
ULBP2，即UL16結(jié)合蛋白2，別名N2DL2、RAET1H、NKG2DL2、ALCAN-alpha。它是一種主要組織相容性復(fù)合體（MHC）I類相關(guān)分子，由人類基因編碼，位于染色體6q25.1上。
ULBP2與自然殺傷（NK）細(xì)胞上的NKG2D受體結(jié)合，觸發(fā)多種細(xì)胞因子和趨化因子的釋放，從而促進(jìn)NK細(xì)胞的募集和激活。許多惡性細(xì)胞會(huì)分泌這種蛋白質(zhì)，以逃避NK細(xì)胞的免疫監(jiān)視。
ULBP2在抗感染免疫、抗腫瘤免疫及自身免疫中發(fā)揮重要作用，它不僅作為NKG2D的功能性配體，還可能通過(guò)TCRγδ1途徑直接激活γδT細(xì)胞，并在抗腫瘤免疫反應(yīng)中發(fā)揮作用。
熱銷產(chǎn)品
Recombinant Human UL16-binding protein 2 (ULBP2), partial (Active) (CSB-AP005521HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ULBP2 Antibody (CSB-PA880151ESR1HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human duodenum tissue using CSB-PA880151ESR1HU at dilution of 1:100
ULBP2 Antibodies
ULBP2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025610GA01HU | ULBP2 Antibody | Human | ELISA,WB |
| CSB-PA880151ESR1HU | ULBP2 Antibody | Human | ELISA, IHC |
ULBP2 Proteins
ULBP2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP880151HU CSB-EP880151HU CSB-BP880151HU CSB-MP880151HU CSB-EP880151HU-B |
Recombinant Human NKG2D ligand 2 (ULBP2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP005521HU | Recombinant Human UL16-binding protein 2 (ULBP2), partial (Active) | Mammalian cell |
