ZBP1
ZBP1，即Z-DNA結合蛋白1，別名DAI、DLM-1、ZBP。它是一種由ZBP1基因編碼的蛋白質，在免疫細胞特別是自然殺傷（NK）細胞中表達。ZBP1的作用機制涉及識別并結合Z-DNA結構，激活下游信號通路，如NF-κB，從而調控炎癥反應和細胞死亡。ZBP1參與了細胞對病原體的免疫應答，特別是通過促進NK細胞的活化和細胞因子的產生來限制病原體的擴散。此外，ZBP1還與細胞凋亡和壞死等程序性細胞死亡過程有關，影響細胞的生存和死亡。ZBP1的功能異常與某些疾病有關，包括自身免疫性疾病和某些類型的癌癥，是免疫學和細胞生物學研究中的一個重要分子靶點。
熱銷產品
Recombinant Human Z-DNA-binding protein 1 (ZBP1) (CSB-EP861990HUb1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ZBP1 Antibodies
ZBP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA026311GA01HU | ZBP1 Antibody | Human | ELISA,WB,IHC |
ZBP1 Proteins
ZBP1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP837712RA CSB-EP837712RA CSB-BP837712RA CSB-MP837712RA CSB-EP837712RA-B |
Recombinant Rat Z-DNA-binding protein 1 (Zbp1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ZBP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP861990HU CSB-BP861990HU CSB-MP861990HU |
Recombinant Human Z-DNA-binding protein 1 (ZBP1) | Yeast Baculovirus Mammalian cell |
| CSB-EP861990HUb1 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HU | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HUb0 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HUf0 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HU-B | Recombinant Human Z-DNA-binding protein 1 (ZBP1), Biotinylated | E.coli |
ZBP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP865587MO CSB-EP865587MO CSB-BP865587MO CSB-EP865587MO-B |
Recombinant Mouse Z-DNA-binding protein 1 (Zbp1) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
