Recombinant Pig Calcitonin gene-related peptide type 1 receptor (CALCRL)

in vitro E.coli expression system

中文名稱：

Recombinant Pig Calcitonin gene-related peptide type 1 receptor(CALCRL)
貨號：

CSB-CF848799PI
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

CALCRL
Uniprot No.：

Q8WN93
別名：

CALCRL; CGRPR; Calcitonin gene-related peptide type 1 receptor; CGRP type 1 receptor; Calcitonin receptor-like receptor
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-462
氨基酸序列

ETEEENPDDLIQLTVTRNKIMTAQYECYQKIMQDPIQQTEGIYCNRTWDGWLCWNDVAAG TESMQHCPDYFQDFDPSEKVTKICDQDGNWFRHPESNRTWTNYTQCNINTHEKVQTALNL FYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSIVTIIHLTAVANN QALVATNPVSCKVFQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWG FPLIPACIHAVARRLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLK VTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILVHYQGLLVS TIYCFFNGEVQAILRRNWNQYKIQFGNSFSHSDALRSASYTVSTISDGAGYSHDYPSEHL NGKSIHDMENIVIKPEKLYD
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
基因功能參考文獻：
1. Data suggest that ADM (adrenomedullin) increases oviductal fluid secretion via chloride secretion by calcium and cAMP signal pathways (not nitric oxide signal pathway) via CGRPR (calcitonin gene-related peptide receptor; not adrenomedullin receptor). PMID: 23966326
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family
組織特異性：

Detected in lung and coronary artery.
數據庫鏈接：

KEGG: ssc:397172

STRING: 9823.ENSSSCP00000016986

UniGene: Ssc.2695